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In recent years, the pathogenic role of iron overload in cardiotoxicity has been widely recognized

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FasL promotes the tumor-specific exclusion of cytotoxic T-cells, facilitates the formation of an immunosuppressive TME, and leads to the development of drug resistance 71 ( Figure 3G )

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Biomed Opt Express , 15 , 60636072

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The liver contains the highest concentration of these enzymes, which is consistent with its primary function as receptor of the majority of the xenobiotics absorbed by the organism

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