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In a study involving SAH model rats, oral administration of CU (10 mg/kg) over the course of 1 week resulted in a significant reduction in glutamate and GLT-1 expression, with malondialdehyde (MDA) levels in the hippocampus and cortical regions decreasing by 18% and 29%, respectively

10.1038/ng0794-433 Nat

In order to test this hypothesis, the group synthesized 2-[[2-[4-(3-oxo-1,2-benzoselenazol-2-yl)phenyl]acetyl]amino]ethyl-triphenyl-phosphonium chloride (mitoperoxidase 2) derivative and evaluated its efficacy for ameliorating radiation toxicity in cellular and mice models (Table 2) (Fig

Micelle-based delivery systems is also effective in the treatment of those diseases with intact BBB structure