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Efficacy of Bacillus coagulans Unique IS2 in treatment of irritable bowel syndrome in children: a double blind, randomised placebo controlled study

While the development of DDSs is inherently complex and time-intensive, their potential advantages, including improved targeting, lower toxicity, and extended circulation time, make them strong contenders in next-generation treatment strategies

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Based on its role in the abovementioned biochemical pathways, it is expected that thiamine deficiency will result in increased oxidative stress and lower cell proliferation, as well as decreased fatty acid synthesis (including myelin) with severe consequences especially during brain development