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Furthermore, in a phase 2 basket trial of anti-PD-1 monotherapy with pembrolizumab, all five enrolled patients with RMC consistently showed progressive disease, with a median time to progression of only 8.7 weeks, irrespective of PD-L1 expression or tumor-infiltrating lymphocyte (TIL) levels 13

Tesamorelin is a unique case, as it is the only secretagogue that the FDA actually approved for specific clinical indications, such as lipodystrophy in HIV patients