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As SARD are highly complex, multifactorial, and heterogeneous diseases, ML is an ideal approach because it can reveal patterns and interactions between variables in large and complex datasets more accurately and efficiently than traditional statistical methods

LuLYangLKYueJWangXSQiJYYangFet alScutellarin alleviates depression-like behaviors induced by LPS in mice partially through inhibition of astrocyte-mediated neuroinflammation

It is also noteworthy that the k cat of the two enzymes also differ by 3-fold, something that we cannot explain using static structures and may involve distinctions in active site motion, as outlined elegantly for other enzyme systems 30

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