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### FICI, Fractional Inhibitory Concentration Index

Cell Death and Diabetic Cardiomyopathy

The coding region for the scFv T84.66 51 was cloned on the pSB19-PapRS#34 plasmid with the OmpA signal sequence for periplasmic secretion as well as a C-terminal Azo-tag (GG-Pap) and produced in NEBExpress(lowRF1) in 500 mL LB/Amp medium

9 This is important because N-terminally truncated isoforms (N), lacking the transactivation domain, retained their DNA-binding domain and could act in a dominant-negative manner either by competing with the TA isoforms of p63 and p53 for DNA-binding sites or by direct protein interaction