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During the inflammatory phase, the release of oxygen radicals by leukocytes, the subsequent lipid peroxidation of cellular and organelle membranes, the disruption of the intracellular matrix, and the alteration of important protein enzymatic processes cause tissue damage [37]

Interestingly, carnitine supplementation resulted in a complete reversal of all the biochemical, gene expression and histopathological changes-induced by SUN to the control values

P., Nissim, I., Brosnan, M

The lysate was then divided into two aliquots: one serving as the control and the other treated with OroA (100 M) at room temperature for 1 h