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17 The NSAID diclofenac undergoes extensive glucuronidation mediated by UGT2B7 and elicits idiosyncratic hepatotoxicity that causes significant mortality if it progresses to jaundice

Any observed sleep-related effects would theoretically be mediated through GH pathway activation rather than direct CNS effects

Antioxidants 12:1199 Chapman JM, Muhlemann JK, Gayomba SR, Muday GK (2019) RBOH-dependent ROS synthesis and ROS scavenging by plant specialized metabolites to modulate plant development and stress responses