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Effects on the respiratory tract 7.1.3

Among the key causative agents, anthracyclines, such as doxorubicin (DOX), are particularly notable, as the severe cardiac damage they inducecharacterized by ventricular dilatation, interstitial fibrosis, and progression to HFsignificantly limits their clinical utility [73]

Nonalcoholic steatohepatitis is the most rapidly increasing indication for liver transplantation in the United States

nucleotide-binding oligomerization domain-like receptors (NLRs), such as NOD-like receptor protein 3 (NLRP3), NLRP4, NLRP6, NLRP10, nucleotide-binding oligomerization domain-containing protein 1 (NOD1), and 2 (NOD2)