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Macrophage-targeted isoniazid-selenium nanoparticles promote antimicrobial immunity and synergize bactericidal destruction of tuberculosis bacilli

The results were ambiguous since only DeepLoc-10 predicts both proteins as being lysosomal (GliT=0.6683 and GtmA=0.4158)

Similar to the genomic, transcriptomic, methylomic and proteomic approaches described above, these functional/empiric approaches rely on homotypic experimental settings, mainly cultured cancer cells, de facto overlooking the notion that CDDP resistance (at least in some settings) might originate from alterations of the tumor microenvironment or systemic defects (see below)

Besides ageing, levels of this antioxidant in the body can also be depleted due to factors like a poor diet and a sedentary lifestyle