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this reduces the enzymatic activity of MTHFR by approximately 35% per T allele , resulting in inefficient production of methylfolate ( Figures 3 and 4)

Additionally, impaired bile flow and altered drug metabolism in hepatic dysfunction can cause drug accumulation in the liver, further elevating the risk of toxicity [86]

Seven days after irradiation, mice were euthanized, and the entire large intestine was carefully excised, starting from the cecum (the distal end of the small intestine) to the anal verge

Efficient recovery of liver function post-injury relies heavily on the activation and regulation of several key signaling pathways