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& Isidoro, C

Int J ChemTech Res

doi: 10.1200/JCO.2014.57.9151 43 KutEMenekseS

Protein binding Clozapine displaces warfarin and digoxin from proteins leading to increased exposure of both drugs Additive Adverse Effects There is a risk of myelosuppression if clozapine is administered alongside other drugs that can cause myelosuppression, such as long acting depot antipsychotics or carbamazepine