chemically modify glutathione agarose Purification of proteins fused to

This was performed in all DOX-containing groups, while control groups received an equivalent volume of saline

Porokhovnik LN, cape BM, yaeo A, Chudakova YuM, Ershova ES, Veiko NN, Gorbachevskaya NL, Mamokhina U, Sorokin A, Basova AY, Lapshin MS, Izhevskaya VL, Kostyuk SV (2023) Association of NEF2L2 Rs35652124 polymorphism with Nrf2 induction and genotoxic stress biomarkers in autism

Consistent with this result, the pharmacological inhibition of mTOR activity in the brain of AD mice was shown to restore autophagy and to reduce A and Tau levels (370373)

This combination of defective mitophagy and impaired protein import exacerbates the proteostatic stress, promotes aggregate formation, and further compromises mitochondrial dynamics