glutathione and anemia Reduced (GSH) adenosine deaminase (ADA) of the G6PD Deficiency • Glucose-6-phosphate dehydrogenase

G6PD Deficiency Glucose 6 phosphate dehydrogenase deficiency X linked recessive disorder Leads to low NADPH, impairing glutathione regeneration RBCs are vulnerable to oxidative damage Pathophysiology: In G6PD deficiency: No anemia glutathione metabolism production and turnover in RBC. Schematically presented are Rasburicase Induced Hemolytic Anemia Secondary to Glutathione synthetase deficiency: MedlinePlus Genetics Glutathione S transferase and catalase gene polymorphisms did not tend to influence the severity of hemoglobin E thalassemia Universa Medicina

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