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Figure 1: Showed the right mandibular edentulous ridge of a patient diagnosed with CTN and the fabricated stent to cover the painful site Pharmacological methods Pharmacological treatments include antidepressants (e.g., SSRIs, SNRIs, TCAs) and anticonvulsants (e.g., gabapentin, carbamazepine), which suppress neuronal hyperexcitability

However, most of this evidence comes from case reports and small observational cohorts, with a conspicuous lack of large-scale prospective trials

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In neurodegenerative diseases, mitochondria are the main source of ROS in cells undergoing ferroptosis (Wu C