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Zhen X, Sun Y, Lin H, Huang Y, Liu T, Li Y, Peng H (2023) Elucidating the role of nicotinamide N -methyltransferase-p53 axis in the progression of chronic kidney disease

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Nevertheless, several key observations in our model, including the reduced number of ciliated cells, the increase in secretory cells, and a loss of cellular resilience in IPF-derived phBECs, are consistent with reported epithelial alterations in IPF in vivo, supporting the value of our model as a meaningful platform for mechanistic investigation 71,72