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While acute cuprizone intoxication in rodents has shown to lead to increased synaptic density in superficial cortical layers, in the subcortical area, such as the dorsal lateral geniculate nucleus, the contrary has been observed

Toxins 9(12):398 Cosovanu C, Neumann C (2020) The many functions of Foxp3 + regulatory T cells in the intestine

pH gradient difference around ischemic brain tissue can serve as a trigger for delivering polyethylene glycol-conjugated urokinase nanogels

Importantly, recent reports showed that about 211% of patients with COVID-19 had underlying chronic liver disease ( The above and other reports led Roberts et al