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One potential strategy to increase access to advanced primary care and prepare practitioners in traditional Medicare to engage in more accountable care is through the creation and ongoing refinement of specific billing and coding under the PFS that better recognizes advanced primary care and incorporates the resources involved in furnishing longitudinal care and maintaining relationships with patients over time

It is studied in laboratory research for its interaction with cell signaling pathways related to tissue-level cell behavior, including nitric oxide signaling and endothelial cell function

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