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Number of clinical trials by year, country, WHO region and income group (1999-2019) | World Health Organization New study shows the rate of drug approvals lower than previously reported | Biotechnology Innovation Organization How long a new drug takes to go through clinical trials | Cancer Research UK International clinical trials day: The voyage of drug discovery | Alzheimers Research UK Clinical development success rates 2006-2015 | Biotechnology Innovation Organization SAE rates in clinical trials | Applied Clinical Trials Charts and statistics | CISCRP Risk and emotion among healthy volunteers in clinical trials (2016) The author, Claire Bonneau, is a medical writer and certified trauma operating room nurse

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Table 4 provides a summary of key determinants of ivermectin pharmacokinetic variability between species and administration conditions and highlights the reasons why dosing choices should be species- and formulation-specific