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This synaptic plasticity process involves several activities that alter synaptic proteins, including glutamate receptors (-amino-3-hydroxyl-5-methyl-4-isoxazole-propionate and N-methyl-D-aspartate (NMDA), postsynaptic density protein 95 (PSD-95), and other kinases such as calmodulin-dependent kinase II (CaMKII) and protein kinase C (PKC), to modify the synaptic structure (Alhowail and Aldubayan, 2023

Generally, the effects of Botox (onabotulinumtoxinA) are consistent, lasting between 3 and 6 months

This is achieved by the elimination of hydrogen peroxide primarily through the dual function of the same egg oxidase, and secondarily through cytoplasmic ROS scavengers, such as catalase and glutathione

Table 1 Small molecule inhibitors that target various pathways in GBM