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Oxidative stress, which can damage cells, proteins, and DNA, is associated with various health conditions

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Early ongoing activity in the brain is dominated by long-lasting, recurrent potentials known as giant depolarizing potentials (GDPs)

In rat depressive model induced by chronic mild stress, Cdk5 activity and p35 trafficking was enhanced in the hippocampal dentate gyrus, which was suppressed by the antidepressant venlafaxine (Zhu et al., 2012)