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A clinical trial of cannabidiol on 15 HD patients showed no improvements in motor function over a 6 weeks period (Consroe et al., , a botanical extract with an equimolecular combination of delta-9-tetrahydrocannabinol and cannabidiol conducted over 12 weeks on 24 HD patients reported no significant symptomatic effects (clinicaltrials.gov ID: NCT01502046

Acta 44 DiX.YanJ.ZhaoY.ZhangJ.ShiZ.ChangY.et al (2010)

[DOI] [PubMed] [Google Scholar] 443.Sharma S., Yang I.V., Schwartz D.A

Methyl donor deficiency impairs fatty acid oxidation through PGC-1alpha hypomethylation and decreased ER-alpha, ERR-alpha, and HNF-4alpha in the rat liver