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Summarizing, NaBPC157 proves useful as an antiarrhythmic, antianginal and cardioprotective agent

Tamoxifen induces apoptosis in P-gp expressing cells To determine if tamoxifen-induced collateral sensitivity of drug resistant cells is due to enhanced apoptosis, AuxB1 and CHO R C5 cells were treated with tamoxifen for 24 h and then examined for the presence of apoptotic cells using FITC-conjugated annexin-V and cell staining with Hoechst Dye

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The inhibition of ISCA2 (a component of the late mitochondrial iron-sulfur cluster assembly complex) reduces the HIF-2 protein level and triggers an iron starvation response, leading to iron/metal overload and contributing to ferroptosis, which is more significant in VHL-defective cells (82)