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Thus, significant levels of illicit drug use were observed in the antisocial men, and the drugs such as cocaine that were detected have been previously found to impact on both GABA and glutamatergic systems [89,90,91,92]

While targeted biochemical analysis reveals direct mediators of specific substrate interactions within a complex, combining these analyses with affinity measurements in the context of multimeric assemblies in complex lysates takes into consideration the possibility of larger molecular regulatory networks

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