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This work was supported by the Natural Science Foundation of Hunan Province (2023JJ30352), the Key Project of Hunan Traditional Chinese Medicine Administration (C2023010), the Excellent Youth Program of Hunan Education Department (22B0091), the Research Project of Health Commission of Hunan Province (202203013494) and the Changsha Natural Science Foundation of China (kq2208116)

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The number appears to derive partly from the saturation dose concept discussed next, and partly from convention propagated across forums and vendor literature until repetition lent it a false air of authority