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Activation of NF-B in endometrial stromal cells leads to increased expression and secretion of inflammatory mediators like ICAM-1, contributing to the pro-inflammatory microenvironment [92]

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Pyuria had been indexed to code N39.0, Urinary tract infection unspecified, so did not have its own unique code

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Future work should prioritize structureactivity relationship (SAR)-guided RPTS analog development, identification of SPI1-targeted inhibitors, and stratification of patients based on SPI1/LCN2 expression profiles

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