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Hui-Hui Chen, [email protected] These authors share first authorship Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Furthermore, HOP1 markedly de-repressed LET7 TPR -mediated inhibition of LET7 PPase phosphatase activity (Fig

Validation of differentially expressed proteins or biomarkers by peptide intensity and ELISA assay quantification To validate the differentially expressed proteins identified in plasma samples across the three groups, we selected CST3, GAPDH, PCSK9, C1QA, CPB2, and PRDX6 based on significant fold changes and pathway enrichment scores