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Enhancing the barrier function of mucus The airway mucus barrier serves as the first line of defence against inhaled particulate matter, including pathogens, allergens and carcinogens

doi: 10.1002/adhm.202400149 93 GopalanD.PandeyA.UdupaN.MutalikS

Co-treatment of LY294002 or MK-2206 with AZD5363 attenuates AZD5363-induced increase in the level of phosphorylated AKT

4.2 Future clinical perspectives Recent work in the field underscores the need for broader and more integrative approaches to AMS therapeutics, recognizing that oxidative stress, inflammation, and disruptions in energy metabolism interact dynamically during exposure to hypobaric hypoxia