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Also, Hcy may elevate ADMA levels by inducing ER stress and cell death, leading to increased proteolysis of proteins that contain methylarginine residues

FEBS Lett 459(1):3338

M.et al (2018)

When combined with CBP, THZ enhances the anti-tumor activity, resulting in significant inhibition of TNBC proliferation, induction of apoptosis, and suppression of tumor growth both in vitro and in vivo