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Glutathione ( 3a ) also reacts with organic electrophiles ( R ), such as several reactive metabolites of environmental contaminants and pharmaceutical drugs, and with metal ions of thiophilic elements ( M ) to yield the corresponding glutathione thioethers ( 5a ), alkyl-cysteines ( 5b ) and mercapturic acids ( 5c )

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[DOI] [PMC free article] [PubMed] [Google Scholar] 218.Ishikita A, Matsushima S, Ikeda S, Okabe K, Nishimura R, Tadokoro T, et al