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Dapagliflozin: a review of its use in patients with type 2 diabetes

CYPs may also catalyze demethylation to aflatoxin P (AFP 1 ) of the parent AFB 1 molecule, resulting in products less toxic than AFB 1

Moreover, although the unmethylated CpGs of lipoplex systems are masked preventing an innate immune response, once they are in the general circulation, lipoplex systems may be, similarly like polyplex systems, opsonized by blood proteins (C3, IgG, lipoproteins and fibronectin) resulting in inflammatory reactions (mediated by TNF-alpha, IL-6 and IL- 12) in lungs and liver