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These mediators comprise interleukin-1 (IL-1), tumor necrosis factor- (TNF-), which shoulder vital responsibility in inflammatory responses ( IL-1, TNF-, and other inflammatory mediators regulate the expression in a variety of cell types like alveolar bone osteoblasts, gingival fibroblasts, amplifying the damage of periodontal tissues and bone resorption processes ( 2.3.2 Cellular dysfunction and apoptosis In gingival tissues, oxidative stress causes lipid peroxidation, protein oxidation, and DNA damage

Comparison of coral resorption and bone apposition with two natural corals of different porosities

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