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2 Results 2.1 MitoQ induces cell death and differentiation in neuroblastoma cells and potentiates DPI-induced cytotoxicity To investigate whether enhanced ROS production mediates the cytotoxic effects of DPI, we used MitoQ, a ROS scavenger that selectively accumulates in mitochondria (27, 28)

In: ACSAP 2015 Book 1Neurologic and Psychiatric Care

[PubMed: 28930626] [CrossRef] 127

In parallel, chemokine-high macrophage subsets expressing CXCL16 and CCL8 orchestrate a second wave of immune infiltration, characterized by CCR1 + neutrophils, macrophages, and CXCR6 + T cells, which damaged TECs again