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After stopping a CYP3A4 inhibitor, as the effects of the inhibitor decline, the oxycodone plasma concentration will decrease [see Clinical Pharmacology], resulting in decreased opioid efficacy or a withdrawal syndrome in patients who had developed physical dependence to Oxycodone and Acetaminophen Tablets

Our previously randomized clinical trial with 60 FD-patients found that compared to once a week, acupuncture with 3 sessions per week was more effective to improve symptoms and quality of life among patients, accompanied by a long-term therapy [78]

Corticosteroid-free clinical remission was defined as the proportion of patients in this subgroup who discontinued corticosteroids by Week 52 and were in clinical remission at Week 52