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(MPG 13825 kb) Supplementary Movie 6 (download AVI 3-D projections showing J774 cells with fluorescent labeled bacterial cells inside

No significant difference in the primary end point, a composite score (NIS-Lower Limbs (NIS-LL) and seven neurophysiological tests), was observed between -lipoic acid treatment and placebo

Whereas emodin 8-glucoside was involved in conventional hydrogen bond interactions with ASP-457, PHE-264, ASP-538, and LEU-566 of TFRC, Pi-anion interactions with ASP-562, and alkyl and Pi-alkyl interactions with LEU-489

But the absence of signals in a relatively small, short-duration trial is not the same as a confirmed long-term safety profile