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Pharmacokinetics: In dogs, the absorption and elimination characteristics of the oral formulation are linear (plasma concentrations increase proportionally with dose) when enrofloxacin is administered at up to 11.5 mg/kg, twice daily.2 Approximately 80% of the orally administered dose enters the systemic circulation unchanged

However, not all intravenous medications can be administered intramuscularly

Routine microsecond molecular dynamics simulations with AMBER on GPUs