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However, there still lacks direct and effective therapeutic interventions to alleviate cisplatin-induced AKI (Cis-AKI) [7]

These enzymes, such as creatine kinase and adenylate kinase, play critical roles in generating the ATP required for sperm motility and the acrosome reaction (77, 78)

Inflammaging is associated with increased susceptibility to infections, autoimmune disorders and various age-related diseases, creating a feedback loop that accelerates the breakdown of immune health and increases morbidity and mortality risks among elderly [3, 4]