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In contrast, individuals with SLE have reduced diversity of gut microbiota, with a structural and functional disorder known as dysbiosis ( Firmicutes and Bacteroidetes together account for approximately 98% of the bacterial community, low F/B ratio is linked to gut microbiota dysbiosis, once more pointing to microbial imbalance as being key to SLE pathogenesis ( SLE patients are usually characterized by a condition called leaky gut, which is compromised integrity of the intestinal barrier

These are structural variants with similar mechanisms, but they are not identical molecules

the isoelectric point (pI) is the pH at which net charge is zero, calculated by averaging the pKa values of the two ionizable groups flanking it

Heller, Cured of Disease, to Assume New Sloan-Kettering Post"