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This susceptibility stems from reduced basal GSH levels caused by impaired plasma membrane expression of SLC7A11

A randomized phase III trial evaluated selenium supplementation in selenium-deficient gynecological cancer patients receiving adjuvant radiotherapy, and it proved effective in reducing the incidence of grade 2 diarrhea, particularly in patients with a large planning target volume (387, 388)

Benefit OPITAC Glutathiones antioxidant advantage It is the ability to scavenge the ROS (Reactive Oxygen Species) through enzymatic reaction that forms the basis of OPITAC Glutathiones supporting antioxidant activity

Cutadapt software 1.18 was utilized for initial data preprocessing, including the removal of Illumina sequencing adapters and poly(A) tail sequences