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Moreover, Virtual screening and system Pharmacology could be an intriguing approach since they can reveal the connections between unexplored drugs and molecular targets linked to OSA pathogenesis, which would eventually decrease the time required for preclinical testing and increase the chances for success of clinical trials [109, 110]( Fig

In contrast, this region is well defined in the final electron density map of PtGSTU20 GSH and PtGSTU20 GSPAP and adopts the same conformation as observed in known GSTU structures including PtGSTU19 APO/GSH