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The administration of this extract to depressed mice prevented dendritic spine loss through the inhibition of 5-HT reuptake, increasing 5-HT brain levels, alleviating the depressive-like behavior of the animals [102]

It works as a key, allowing the sugar to go from the blood and into the cell

A recent study has documented that in patients over 65 years, a low TSH level from either endogenous or exogenous thyrotoxicosis is associated with higher risk of incident cognitive disorders (313)

Future research integrating multi-omics approaches, such as metagenomics, metabolomics, and host transcriptomics, together with large-scale longitudinal studies and well-designed clinical trials, will be essential to clarify causal mechanisms and evaluate the long-term efficacy of microbiome-targeted interventions