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The glutathione peroxidase activity of glutathione S-transferases

453 In summary, although targeted therapy has significantly improved the prognosis of various tumors, drug resistance remains a major challenge

IL-8interleukin 8

The subsequent buildup of lipofuscin, characteristic of lysosomal aggregates, is associated with metabolic disruptions and impaired autophagic function, establishing it as a key biomarker for cellular aging 29