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Biological Trace Element Research, 186(1), 5267

In more complex or persistent cases, specialists may explore options like steroids, IVIG (intravenous immunoglobulin), or in rare instances, therapeutic plasma exchange (6)

Additionally, HIF-1 increases ceruloplasmin, which promotes the oxidation of Fe 2+ to Fe 3+ , facilitating the efflux of iron from cells (Yang et al., 2025)