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A patient's lack of understanding of clinical care instructions provided after a procedure and other aspects of health literacy have been linked to poor adherence to treatment, decreased patient safety, increased return to the emergency department, and lower levels of patient satisfaction

The connection between thyroid function and intestinal microbiota has been suggested in animal models since the 1970s, and intestinal dysbiosis has been reported to influence iodide absorption and enterohepatic circulation from the intestinal lumen, both of which have an impact on thyroid hormone amounts