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Clinical observations on individuals with pernicious anaemia suggests that intra-muscular treatment with high-dose vitamin B12 over a period of a few weeks typically resolves the neurological symptoms in most cases [9, 10], suggesting a reversible biochemical state, and not an irreversible degeneration or loss as seen in some forms of dementia

International journal of molecular sciences, 20(6), 1305

It has never received FDA approval for human use, and standard drug screens generally do not include assays for peptides like BPC-157

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