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Current therapeutic options include psychotherapy (such as cognitive behavioral therapy), pharmacotherapy (such as antidepressants and anxiolytics) and hormone replacement therapy (HRT)

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The crystal structures of the complex made up of the C1 cyclase homology domain (CHD) from AC5 and the C2 CHD from AC2 (VC 1 :IIC 2 ) bound to FSK and GTP-S-activated Gs served as the fundamental model for the prototype AC catalytic core (Mou et al., 2009)