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doi:10.1007/s11102-018-0891-5 Xu G, Chen J, Lu B, Sethupathy P, Qian WJ, Shalev A

These iron ions are taken up by cells through TF and its receptors, leading to intracellular iron accumulation, which catalyzes iron-dependent Fenton reactions, producing excessive ROS that cause lipid peroxidation and membrane damage (Meng et al., 2017