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Excessive ROS oxidizes DNA bases, notably converting guanine into 8-hydroxy-2-deoxyguanosine (8-OHdG) [73]

Targeting Syndecan1 to overcome acquired resistant to KRAS inhibitor in gastrointestinal cancer

These activities further improve the renal inflammatory microenvironment and inhibit reactive oxygen species (ROS) generation and renal cell proliferation (9)