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Excess ROS can damage all major cellular constituents (DNA, proteins, and lipids) and even lead to cell death, apoptosis, hypertrophy, fibrosis, and contractile dysfunction in the myocardium [8, 11]

Moreover, as mentioned, beta-amyloid has other functions than just helping to fight off infection, and in small amounts both beta-amyloid 40 and beta-amyloid 42 promote neuronal survival ( APOE variants and amyloids, then, depends on circumstances like diet and pathogen exposure

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