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The ATF6 signaling pathway mediates inflammation The ATF6 signaling pathway plays a significant role in mediating inflammation, particularly in the context of ER stress and various inflammatory conditions

Analyses of TNF-, IL-6, P16 gene expressions After analyzing the raw data of real-time PCR and analysis of expression fold change, our findings showed that the level of IL-6 (P 0.014

Additionally, combination regimens that optimize efficacy while minimizing cumulative hepatic burden and the evaluation of hepatoprotective adjuvants warrant further investigation

Therefore, in future, special attention should be paid to the adverse reactions or intolerance of BBR in the drug development